Record: 5-9 - Home: 3-4 - Road: 2-5
- 1999: Randy Johnson returned to his old stomping ground in Seattle for the first time in an Arizona uniform, and pitched a complete-game shutout, as the Diamondbacks beat the Mariners 6-0. He scattered eight hits, walked none and struck out 10 in a 139-pitch effort. [He'd throw 139 more in his next start, five days later!] Tony Womack and Matt Williams had two-run singles in a four-run D-backs sixth, with Bernard Gilkey delivering a two-run shot in the eighth. David Delluci and Andy Fox each had three hits for Arizona.
- 2001: Miguel Batista and Arizona came out on the wrong end of a pitching duel against future D-back Livan Hernandez, losing 1-0 to the Giants in San Francisco. The visitors managed only three hits in total, but San Francisco were little better, getting only four off Batista, Greg Swindell and Bret Prinz. Neither side managed a hit with runners in scoring position, the sole run coming when Ramon Martinez homered on the first pitch he saw in the bottom of the third inning. Arizona's best chance was the sixth, when Craig Counsell singled, and stole second with one out, but was stranded.
- 2006: Brandon Webb improved to 11-3, throwing eight strong innings as the Diamondbacks beat the Dodgers 5-2 at Chase Field. He scattered seven hits and two walks, with four strikeouts, allowing both runs as earned. Conor Jackson got Arizona on the board with an RBI single in the first; Los Angeles tied it up immediately, but RBI hits from Stephen Drew and Orlando Hudson in the second put the D-backs ahead to stay. Chad Tracy and Drew each had a couple of hits, and Carlos Quentin delivered his first long-ball of the season, a two-run shot.
- 2011: A two-run double in the eighth inning, off the bat of Willie Bloomquist, tied the game against the Brewers at Chase Field, with the score 2-2, and forced extra innings. However, Milwaukee scored three in the 10th, and the visitors won 5-2. Cook failed to retire any of the four batters he faced in his first-ever game, becoming only the fifth pitcher since 1918 to debut with 3+ ER and the loss, without recording an out. Justin Upton and Kelly Johnson had two hits apiece, while Joe Saunders allowed two runs in seven innings.